PE-22-28 10mg research vial
PE-22-28 10mg research vial: a seven amino acid peptide trimmed down from spadin, a natural peptide cut from the protein sortilin, for 2,300,000 VND ($90 USD).
For PE-22-28, this page sums up one review (2019) and two animal studies (2010 and 2017) from PubMed, none of them in people; one French team did most of the work, its weak point.
2,300,000 VND ($90 USD)1 vial
USD prices are the store's dollar prices; you pay the VND price.
- Free delivery anywhere in Vietnam, no minimum order
- Ships with bacteriostatic water and a container
- Research Use Only. Not an approved medicine.
A Seven Amino Acid Cut of Spadin
Spadin is a 17 amino acid piece cut from a protein called sortilin, and it blocks TREK-1, a potassium channel in nerve cells. Shortening spadin to seven amino acids gave PE-22-28.
One team, at the Institute of Molecular and Cellular Pharmacology in Valbonne, France, produced most of the research.
| Group | Neuropeptides and analogues |
|---|---|
| What it is | Spadin fragment |
| Vial | 10mg vial, Research Use Only label |
Cell and Mouse Work, Mostly One French Team
Cell and mouse studies, mostly from that one French team, plus one review. No studies in people.
What to weigh: The animal work here uses mouse screening tests, run mostly by one team, which is where early research begins rather than ends.
- Animal study, 2010 Model: mice given spadin, the larger peptide it comes from, in the paper that first described it.Measured: behavior in 5 standard tests used to screen antidepressants.
- Animal study, 2017 Model: mice given shortened spadin versions, PE-22-28 among them.Measured: how strongly each version blocked TREK-1, how long it lasted in the body, and behavior in the same screening tests.
- Review, 2019 Scope: spadin and its short versions as TREK-1 blockers.Based on: mouse studies, and how long spadin lasts in the body.
Screening tests such as the forced swim test pick compounds for more study. They do not show an effect in people.
Sources: PubMed 20405001 (PLoS biology, 2010); PubMed 28955242 (Frontiers in pharmacology, 2017); PubMed 30291907 (Pharmacology & therapeutics, 2019).
Buyer Questions About PE-22-28
What does TREK-1 do?
It is a potassium channel in nerve cells. Spadin and PE-22-28 block it, and that block is what their research studies.Is there human research on PE-22-28?
No. The studies found are cell and mouse work, mostly from one French team, plus one review.What is spadin?
A 17 amino acid piece of the protein sortilin. It breaks down within hours, which is why shorter versions were made and tested for stability.Who runs most PE-22-28 research?
A team at the Institute of Molecular and Cellular Pharmacology in Valbonne, part of the French research body CNRS.Does the forced swim test show an effect in people?
No. It is a mouse screening test that picks compounds for further study.
PE-22-28 Pack Prices and Delivery
At 2,300,000 VND ($90 USD), PE-22-28 is the cheapest 10mg vial in its group; per mg that is 230,000 VND ($9.00 USD), or 138,000 VND ($5.40 USD) bought ten at once.
| 1 vial | 3 vials | 5 vials | 10 vials | |
|---|---|---|---|---|
| Per vial | 2,300,000 VND ($90 USD) | 1,863,000 VND ($72.90 USD) | 1,656,000 VND ($64.80 USD) | 1,380,000 VND ($54 USD) |
| Per mg | 230,000 VND ($9.00 USD) | 186,300 VND ($7.29 USD) | 165,600 VND ($6.48 USD) | 138,000 VND ($5.40 USD) |
P21 is another neuropeptide analogue tested mainly in rodents, while Semax has small human studies from Russia. DSIP has two small human studies of its own.
Pick a pack, add it to the cart, then tap Checkout on WhatsApp. WhatsApp opens with your order written out, and a real person replies there to confirm the order and how to pay. Nothing is paid on this site.
Delivery is free with no minimum order. In Ho Chi Minh City it is same day when you order by 7pm. Everywhere else in Vietnam it takes 1 to 3 days, with tracking, and the tracking number comes to you on WhatsApp.
Each PE-22-28 10mg vial ships with bacteriostatic water and a container, and it carries a Research Use Only label. When the parcel arrives, check each vial against the lines of your order message.
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